CORDIS Project
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This project aims to develop small molecules that stabilize protein-protein interactions, specifically targeting 14-3-3 proteins linked to cancer and neurodegenerative diseases. By enhancing these interactions, the project seeks to create novel therapeutic strategies for conditions like Alzheimer's and Parkinson's.
The objective of the application is the development and characterization of small molecule stabilizers of protein-protein interactions (“Molecular Glues”) as a novel class of biological tool compounds and potential therapeutic drugs for the treatment of cancer as well as Alzheimer’s and Parkinson’s Disease, respectively.
As biological targets we work on 14-3-3 proteins, an important class of adapter proteins that regulate a multitude of enzymes and proteins involved in the development of cancer…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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Germany, Dortmund
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
Sweden, Umea
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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