CORDIS Project
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This project focuses on advancing optogenetics by developing a miniaturized two-photon system for precise control of neuronal circuits in non-human primates. It aims to enhance our understanding of complex brain functions by enabling wireless optical manipulation of brain activity.
The revolution in optogenetics began with the discovery of light-sensitive microbial opsins and their use to control neuronal activity with cell-type specificity, allowing for the first time functional mapping of the brain with cell type specificity.
However, the wide-field illumination traditionally used in optogenetics synchronously activates large populations of neurons, lacking the precision needed to reproduce the complex, natural firing patterns of neural circuits.
To overcome this limitat…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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