CORDIS Project
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This project investigates the mechanisms of neuron degeneration in Parkinson's disease using a Drosophila model. It aims to understand the progressive loss of dopamine neurons and the factors that trigger this degeneration, potentially leading to new therapeutic strategies.
Parkinson’s disease (PD) is the second most common neurodegenerative disorder primarily caused by the progressive loss of dopaminergic (DA) neurons in the substantia nigra (SN).
Despite the advances in gene discovery associated with PD, the knowledge of the PD pathogenesis is largely limited to the involvement of these genes in the generic cell death pathways, and why degeneration is specific to DA neurons and why the degeneration is progressive remain enigmatic.
Broad goal of our work is theref…
UNIVERSITE DE GENEVE
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Switzerland, Bern
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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