CORDIS Project
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This project explores advanced Force Microscopy techniques to visualize the 3D structure of cell nuclei. By utilizing ultrasound waves and innovative cantilevers, it aims to achieve high-resolution imaging of subsurface structures, enhancing our understanding of cellular architecture.
I propose to pursue two emerging Force Microscopy techniques that allow measuring structural properties below the surface of the specimen.
Whereas Force Microscopy (most commonly known under the name AFM) is usually limited to measuring the surface topography and surface properties of a specimen, I will demonstrate that Force Microscopy can achieve true 3D images of the structure of the cell nucleus.
In Ultrasound Force Microscopy, an ultrasound wave is launched from below towards the surface of…
UNIVERSITEIT LEIDEN
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