CORDIS Project
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This project focuses on developing a high-throughput system for drug discovery using miniaturized 3D cardiac models. By integrating human stem cell-derived cardiac cells with microfluidic technology, it aims to improve the accuracy of drug testing for cardiovascular diseases.
1.Cardiovascular disease is the number 1 cause of death worldwide.
Novel cardiovascular drugs have a high failure rate of 91% in clinical trials.
This failure rate is due to lack of proper cardiac models used to find new drugs.
Drug discovery studies rely mainly on 2D culture models, which have insufficient predictive value of the human heart. A new in vitro 3D model has been developed by assembling human cardiomyocytes into a three-dimensional strip configuration (3D cardiac strip) that better…
RIVER BIOMEDICS B.V.
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