CORDIS Project
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This project focuses on developing a targeted mRNA-based immunotherapy for breast cancer brain metastases. It aims to overcome treatment barriers using lipid nanoparticles and advanced 3D models to enhance understanding of tumor behavior and therapy effectiveness.
Breast Cancer Brain Metastases (BC-BM) signifies second most common (30%) among all cancers, majorly effecting women population in the age group 45-69, and almost 40% of BC patients have been diagnosed with BC-BM during BC disease conditions.
Conventional BC-BM management (chemo + radiotherapy), despite of progression into loco-regional therapies, have showed major limitations for effective management of BC-BM includes blood–brain barrier (BBB) in brain and substantial diagnosis at preliminary s…
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