CORDIS Project
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This project investigates how the spatial organization of genes within the nucleus affects their regulation. By combining advanced imaging and modeling techniques, it aims to reveal the dynamics of gene interactions and their implications for cellular function.
This project investigates the two-way relationship between spatio-temporal genome organization and coordinated gene regulation, through an approach at the interface between physics, computer science and biology.In the nucleus, preferred positions are observed from chromosomes to single genes, in relation to normal and pathological cellular states.
Evidence indicates a complex spatio-temporal coupling between co-regulated genes: e.g. certain genes cluster spatially when responding to similar fact…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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