CORDIS Project
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This project investigates how the three-dimensional structure of genomes influences gene regulation in response to external signals. By creating detailed models of genome organization in various cell types, the research aims to reveal the dynamic relationship between genome architecture and gene expression.
The classical view of genomes as linear sequences has been replaced by a vision of nuclear organization that is both dynamic and complex, with chromosomes and genes non-randomly positioned in the nucleus.
Process compartmentalization and spatial location of genes modulate the transcriptional output of the genomes.
However, how the interplay between genome structure and gene regulation is established and maintained is still unclear.
The aim of this project is to explore whether the genome 3D stru…
FUNDACIO CENTRE DE REGULACIO GENOMICA
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