CORDIS Project
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The 4DCellFate project investigates how specific protein complexes influence the differentiation of embryonic stem cells and their role in cancer. By combining various scientific techniques, it aims to enhance understanding of cell fate mechanisms and develop new therapeutic strategies for complex diseases.
Embryonic stem (ES) cells have the potential to differentiate into any type of cell as well as to renew indefinitely in culture.
They hold great potential for the development of personalized medicines.
However, the molecular mechanisms underpinning cell fate decisions by individual cells are poorly understood.
There is compelling evidence that two large multi-protein machines, the Nucleosome Remodelling and Deacetylation (NuRD) complex and the Polycomb Repressive Complexes (PRCs), modulate chrom…
FUNDACIO CENTRE DE REGULACIO GENOMICA
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom, Cambridge
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Denmark, Kobenhavn
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Utrecht
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Belgium, Antwerpen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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