CORDIS Project
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A-PARADDISE focuses on developing new drug candidates against parasitic diseases like schistosomiasis and malaria. The project employs a target-based strategy to identify and optimize inhibitors of specific enzymes involved in parasite survival.
This proposal builds on the proven methodology developed in the SEtTReND FP7 project to develop inhibitors of schistosome HME as lead compounds for new drugs.
We will employ a target-based strategy for the development of novel drug leads against schistosomiasis, leishmaniasis, Chagas disease and malaria by targeting histone modifying enzymes (HME), in particular those involved in acetylation/deacetylation and methylation/demethylation.
The principal objectives of A-PARADDISE are:- The identifica…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Illkirch Graffenstaden
Type: Research institute
Activity type: Research Organisations
SME: No
Germany, Halle
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Brazil, Rio De Janeiro
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Brazil, Sao Paulo Sp
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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