CORDIS Project
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This project investigates the role of soluble amyloid beta in Alzheimer's disease by using transgenic mice and advanced imaging techniques. It aims to link cellular pathology to neuronal activity and behavioral impairments, exploring potential pharmacological interventions to mitigate memory deficits.
Alzheimer’s disease (AD) is characterised by a gradual cognitive decline, which initially affects learning and memory, and gradually impairs other cognitive functions.
Despite considerable scientific effort, the cause and pathogenesis of AD is still unknown.
Recent in vitro studies suggest that the destruction of synapses by soluble aggregates of amyloid beta (Abeta) might play a role in mediating the progression of the disease.
However, what is lacking is an approach that establishes the links…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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