CORDIS Project
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The ABlina project examines how the composition of cell membranes influences the formation of beta amyloid aggregates, which are linked to Alzheimer's disease. By simulating various lipid environments, it seeks to identify lipid patterns that could lead to new therapeutic strategies.
The ABlina project aims to study how cell membrane lipid composition affects the formation and deposition of beta amyloid (Aβ) aggregates.
To achieve this, Molecular Dynamics (MD) simulations will be performed on membranes with varying lipid compositions, focusing on models that mimic senescent and Alzheimer's disease cells.
The data generated will contribute to the establishment of a database, which will be subsequently analysed, to identify lipid patterns capable of modulating the behaviour of…
UNIVERSIDADE NOVA DE LISBOA
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