CORDIS Project
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This research focuses on arterial calcification caused by inflammation, investigating the role of specific biomarkers and the effects of anticoagulants and oxidative stress. The goal is to identify mechanisms that could lead to new treatments for cardiovascular diseases.
Arterial calcification is a morbid complication of inflammatory disease causing calcium deposition along arterial walls.
Sheer stresses on cellular components affect regenerative capabilities of specific cells, culminating in vessel constriction, compromised wall elasticity and reduced blood flow.
The net effect of restricted blood flow is debilitating and can cause cardiovascular disease, end stage renal disease or peripheral arterial disease.
Animal models have uncovered biomarkers involved in…
WATERFORD INSTITUTE OF TECHNOLOGY
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