CORDIS Project
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This project investigates how tissues develop and pattern during embryogenesis, focusing on the roles of signaling molecules in zebrafish and mouse models. It aims to uncover mechanisms of self-organization and develop synthetic systems for tissue engineering.
A central problem in developmental biology is to understand how tissues are patterned in time and space - how do identical cells differentiate to form the adult body plan?
Patterns often arise from prior asymmetries in developing embryos, but there is also increasing evidence for self-organizing mechanisms that can break the symmetry of an initially homogeneous cell population.
These patterning processes are mediated by a small number of signaling molecules, including the TGF- superfamily member…
UNIVERSITAT KONSTANZ
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