CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project examines the formation of the meiotic spindle in mouse oocytes, focusing on the role of Polo-like kinase 4 in acentriolar cells. It aims to understand the mechanisms of spindle assembly and the behavior of microtubule organizing centers during early embryonic development.
An increase in the age of onset of child-bearing increases in developed countries is leading to an increased incidence of chromosome abnormalities arising in defective meiosis.
Accurate chromosome segregation requires a correctly assembled meiotic spindle and so it is essential to understand this process.
Here we propose to examine how the spindle forms in the oocytes and early embryos of the mouse that, like human oocytes, lack centrioles.
Nevertheless, spindle formation in these cells require…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
