CORDIS Project
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This project aims to create a detailed model of how naïve CD8+ T cells develop into effector and memory cells, focusing on their fate choices and responses to infections. It combines experimental immunology with systems biology to explore the roles of specific proteins in T-cell differentiation, ultimately enhancing va…
Antigen-stimulated naïve CD8+ T cells proliferate and differentiate into effector and memory cells.
Whereas effector T cells remove infected or cancerous cells, memory T cells protect the organism from re-infections.
Despite decades of research, the challenging central questions of how naïve T cells form diverse progeny and what drives the differential response of naïve and memory T cells to infection remain unanswered, largely because of lacking experimental tools.The goal of this project is to…
UMG INSTITUTE OF MOLECULAR GENETICS ACA SCIEN CZECH REPU
USTAV MOLEKULARNI GENETIKY AV CR V.V.I.
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