CORDIS Project
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The project investigates the role of gut microbiota in Alzheimer’s disease, revealing that modulation of gut bacteria can influence disease progression. It aims to develop probiotic strategies for prevention and diagnosis of Alzheimer’s through gut health.
Alzheimer’s disease (AD) is the leading cause of dementia in the Western world and to date no cure nor any preventive strategy are available for this neurodegenerative disorder.
Bacterial 16S rRNA sequencing from fecal samples revealed a remarkable shift in the gut microbiota of conventionally-raised AD mice compared to healthy, wild-type mice.
Based on these findings, we generated germ-free Alzheimer (GF-AD) mouse model and discovered a drastic reduction of cerebral Aβ amyloid pathology when co…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Belgium, Leuven
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
VLAAMS INSTITUUT BIOTECHNOLOGIE FLANDERS INSTITUTE FOR BIOTECHNOLOGY
Belgium, ZWIJNAARDE - GENT
Type: Research institute
Activity type: Research Organisations
SME: No
Sweden, Lund
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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