CORDIS Project
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This project focuses on developing novel immunotherapies for Alzheimer's disease by targeting disease-associated microglia, which are immune cells in the brain. The aim is to enhance the brain's natural defenses against neurodegeneration, addressing the urgent need for effective treatments.
Alzheimer's disease (AD) is a heterogeneous disease in which multiple detrimental factors contribute to cognitive loss and disease escalation.
Currently there are no effective therapies for AD.
Targeting any single symptom of disease-escalating factor (e.g. amyloid beta, tau, neuroinflammation etc.), even if successful, is not sufficient to modify the disease, as seen in the multiple failures of recent phase-III clinical trials.
Thus, there is a desperate need for new approaches for development…
WEIZMANN INSTITUTE OF SCIENCE
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