CORDIS Project
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This project investigates how immune cells, particularly naïve CD4+ T cells, adapt to specific organs and how this adaptation may contribute to organ-specific inflammatory diseases. By analyzing human organs and using advanced technologies, the project aims to uncover the mechanisms behind these diseases and their link…
Organ-specific immune-mediated inflammatory diseases (IMIDs) have a growing socio-economic impact due to their steadily increasing incidence.
At least two aspects are still unclear: what immunological mechanisms restrict these diseases to one or a set of specific organs and what triggers the continuously increasing incidence, particularly in industrialized countries.
Increasing exposure to harmful environmental triggers, such as pollution but also Western diet, have been suggested as potential r…
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
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