CORDIS Project
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This project investigates the role of adenosine, a signaling molecule, in placental development and amino acid transport during pregnancy. It aims to understand how hypoxia affects fetal growth and the implications for infants with intrauterine growth restriction.
Altered fetal growth patterns, i.e. reduced growth in utero (intrauterine growth restriction, IUGR) are associated with perinatal morbidity as well as adverse consequences in adult life, e.g. cardiovascular disease.
A prevailing hypothesis regarding the pathogenesis of reduced growth in utero is the “ischemic model” where abnormal placental bed vascular pathology with reduced nutrient and oxygen delivery to the intervillus space as a result of diminished placental perfusion contributes to subopt…
MEDIZINISCHE HOCHSCHULE HANNOVER
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