CORDIS Project
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AFHELO is investigating a small molecule, AF243, to treat hearing impairment by promoting the differentiation of inner ear cells. The project aims to develop therapies for noise-induced and age-related hearing loss through preclinical studies.
Approximately 10% of the global population (40% of people over 65), suffers hearing difficulties.
The socio-economic impact is deep, since in children, early hearing impairment (HI) affects language learning, and in adults, acquired HI impairs social integration.
The sense of hearing depends upon the integrity of the sensory epithelia in the inner ear. HI occurs when this tissue is disrupted, that is when the sensory hair cells (HC) die and the spiral ganglion neurons (SGN) subsequently degenera…
AFFICHEM SA
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Belgium, Liege
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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