CORDIS Project
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This project explores how layered double hydroxide nanoparticles, made from metal ions, can enhance vaccine effectiveness by improving immune responses. It aims to understand the mechanisms behind their adjuvant properties and their interactions with immune receptors using advanced imaging techniques.
Layered double hydroxides nanoparticles (LDH NPs) composed by divalent/trivalent metal ions are efficient vaccine adjuvants to assist antigens to induce potent humoral and cellular immunity.
However, the adjuvant mechanisms of LDH NPs still remains elusive.
Since the metal ion species and ratio are closely related to the adjuvant activity of LDH NPs, this study will investigate how the metal ion composition will affect the adjuvant activity of LDH NPs.
Then, an atomic force microscopy (AFM)-base…
AARHUS UNIVERSITET
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