CORDIS Project
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This research explores the development of ectopic fat in ageing, focusing on the regulatory cues that control adipogenic progenitor cells. By studying stem cell dynamics, the project aims to uncover mechanisms behind metabolic diseases linked to ageing.
Ageing is accompanied by ectopic white adipose tissue depositions in skeletal muscle and other anatomical locations, such as brown adipose tissue and the bone marrow.
Ectopic fat accrual contributes to organ dysfunction, systemic insulin resistance, and other perturbations that have been implicated in metabolic diseases.This research proposal aims to identify the regulatory cues that control the development of ectopic progenitor cells that give rise to this type of fat.
It is hypothesized that a…
DEUTSCHES INSTITUT FUER ERNAEHRUNGSFORSCHUNG POTSDAM REHBRUECKE
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