CORDIS Project
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This research explores how aging affects protein aggregation, which is linked to various diseases. By studying the model organism Caenorhabditis elegans, the project aims to identify mechanisms that maintain protein function and prevent age-related diseases.
Aging is a major risk factor for neurodegeneration, cancer and heart disease.
Understanding what goes wrong with age, in particular how the proteome becomes dysfunctional may help to slow down or prevent these age-dependent diseases.
Until recently, it was widely assumed that protein aggregation was mainly restricted to the extensive aggregation of a few hallmark proteins in diseases such as neurodegeneration and systemic amyloidosis.
However, we have demonstrated using the model organism Caenor…
DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV
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