CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the role of the MOAG-4 protein in the aggregation of pathogenic proteins associated with neurodegenerative diseases. By identifying interacting proteins, the research aims to clarify the mechanisms of protein aggregation and its implications for aging and disease.
Several age-related neurodegenerative disorders, such as Alzheimer’s, Parkinson’s and Huntington’s diseases, are characterized by the formation of pathogenic proteins aggregates in the brain.
Although some regulators have been identified, how aggregates form during aging is poorly understood.Recently, a modifier of aggregation, MOAG-4, was identified as a positive regulator of aggregation in C. elegans models for neurodegenerative diseases.
The role of MOAG-4 is evolutionarily conserved in the h…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
