CORDIS Project
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This project focuses on improving our understanding of immune responses by developing advanced models for analyzing immune receptor interactions. It aims to enhance vaccine and therapeutic design by accurately predicting how immune receptors recognize antigens.
B- and T- cell adaptive immune receptor (AIR) repertoires are highly diverse, enabling response to a wide range of pathogens.
While sequencing of an individual's immune repertoires is becoming common, our ability to convert these datasets into comprehensive antigen exposure information to inform clinical decisions is limited.
The major challenges are to identify the antigens recognized by B-cell and T-cell immune receptors (BCRs/antibodies and TCRs), model their structures and determine their ep…
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