CORDIS Project
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This project focuses on developing a new chemical synthesis method called 'Assembly Line Synthesis' to create complex carbon chains with precise control over their structure and function. The methodology aims to simplify the synthesis of biologically relevant molecules, including potential tuberculosis antigens.
This proposal seeks to develop a new strategy for chemical synthesis which we term “Assembly Line Synthesis”.
Our plan is to develop new reactions and strategies which enable us to essentially grow a carbon chain with complete control over its shape (stereochemistry) and functionality (which groups are incorporated) in a single operation.
Our unique methodology involves the reaction between a lithiated carbamate and a boronic ester to give the homologated product.
This chemistry can be done in…
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