CORDIS Project
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This project investigates the role of a specific protein, alpha calcium/calmodulin-dependent kinase II, in alcohol addiction by examining its effects on actin remodeling in the brain. Through behavioral studies and molecular analyses in mutant mice, the research aims to uncover the mechanisms that influence alcohol con…
Understanding molecular basis of alcohol addiction still remains a great challenge for science and at the same time the only chance for designing successful molecular therapy.
Calcium and calmoduline-dependent kinase II alpha (alpha CaMKII) is a major protein of forebrain glutamatergic neurons with well established function in various aspects of cell physiology, e.g. actin remodelling.
Alcohol-induced actin remodelling has been recently implicated in control of alcohol resistance and consumption…
INSTYTUT BIOLOGII DOSWIADCZALNEJ IM. M. NENCKIEGO POLSKIEJ AKADEMII NAUK
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