CORDIS Project
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This project investigates the differences in embryonic development speed among species by analyzing pluripotent stem cells. It focuses on the molecular mechanisms behind slower biochemical reactions in human cells compared to mouse cells, using advanced technologies to explore these differences across various mammalian…
While the mechanisms of embryonic development are well conserved, the progression speed differs among animal species.
The molecular cause of ‘allochrony’, interspecies differences in developmental tempo, remains unclear due to lack of an appropriate experimental model.
In vitro differentiation of pluripotent stem cells (PSCs) offers unique opportunities to compare the same cell type among diverse species in a similar condition.
We have previously recapitulated the oscillatory gene expression of…
TECHNISCHE UNIVERSITAET DRESDEN
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