CORDIS Project
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This project focuses on developing new drug candidates to target the interactions between copper ions and amyloid-beta peptides, which are implicated in Alzheimer's disease. The goal is to design compounds that selectively remove copper while preserving the role of zinc in neurotransmission.
Alzheimer's disease (AD) is one of the most serious diseases mankind is now facing as its social and economical impacts are increasing fastly. AD is very complex and the amyloid-β (Aβ) peptide as well as metallic ions (mainly copper and zinc) have been linked to its aetiology.
While the deleterious impact of Cu is widely acknowledged, intervention of Zn is certain but still needs to be figured out.
The main objective of the present proposal, which is strongly anchored in the bio-inorganic…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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France, Strasbourg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
UNIVERSITE TOULOUSE III - Paul Sabatier
France, Toulouse Cedex 9
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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