CORDIS Project
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This project investigates the molecular machinery of bacterial flagellar motors to understand their assembly, function, and evolution. Using advanced imaging techniques, it aims to reveal insights into how these machines generate force and adapt over time.
Life has evolved many molecular machines to perform mechanical tasks.
Studying these machines promises insights into how machinery can generate force, how they assemble themselves, and how they evolved from simpler components.
Ultimately this knowledge may inform synthetic biology projects to redesign existing, or evolve novel, machinery.
Yet these insights have been hindered by our inability to visualize these machines as they occur in situ.
The emergent technique of electron cryo-tomography, h…
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