CORDIS Project
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This project aims to establish the cephalochordate amphioxus as a model for studying regeneration. By investigating its regenerative capabilities and the underlying biological mechanisms, the research could provide insights into potential applications in regenerative medicine.
While the ability to regenerate lost body parts or organs is legendary in invertebrates like echinoderms, chordates-and mammals in particular-have quite limited regenerative ability.
The exceptions par excellence are salamanders, which can regenerate lens, limbs and tails.
Unfortunately, vertebrate models of regeneration are costly to maintain, suffer from necessary ethical considerations, and are often plagued by duplicated genes, hindering functional analyses.
The invertebrate cephalochordate…
UNIVERSITAT DE BARCELONA
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