CORDIS Project
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This project investigates the factors contributing to muscle decline and sarcopenia in aging populations. It aims to identify genetic determinants and molecular pathways involved in muscle aging and protein aggregation, potentially leading to preventive strategies.
After the age of 30, our muscle strength declines by ~14% per decade.
In up to 40% of the elderly, this decline culminates in sarcopenia (SP), critically low muscle mass, causing impaired mobility and longer hospitalizations.
Muscle decline rates vary greatly between individuals due to genetic and environmental factors.
Yet, our lack of insight into these factors impedes developing effective measures against SP. SP is clinically similar to inclusion body myositis (IBM), the most common myopathy…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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