CORDIS Project
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This project investigates nuclear receptors, which are proteins that regulate gene expression in response to hormones and other signals. It aims to develop a comprehensive model of nuclear receptor signaling pathways to understand their roles in health and disease.
Nuclear receptors (NR) are transcription factors activated by nuclear hormones, dietary components and xenobiotics.
Nucleo-cytoplasmic shuttling is an important part of NR signalling:
NR nucleo-cytoplasmic shuttling is regulated by external NR ligands and different intra-cellular processes.In close collaboration with experimental groups within the Marie Curie RTN NucSys (Sept 2007-Sept 2009) we have build a mechanism based kinetic model, integrating nucleo-cytoplasmic shuttling and signalling pr…
VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG
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