CORDIS Project
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This project investigates the regulation of glycogen synthase and its role in various health conditions. It aims to understand how glycogen accumulation leads to cell death and explore potential therapeutic strategies for related diseases.
Glucose is stored in specialized tissues (mainly liver and muscle) in the form of a branched polymer called glycogen.
Glycogen Synthase is the only enzyme able to catalyze this polymerization and its two isoforms (LGS and MGS) are mainly expressed in liver and in muscle, respectively.
However, MGS is also expressed in all other tissues, regardless of their limited capacity to produce Glycogen. MGS activity is tightly controlled by several mechanisms.
Recent results from the receiving group show…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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