CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project focuses on developing inhibitors for bacterial histidine-kinase as new broad-spectrum antibacterial agents. It aims to identify mechanisms of resistance and potential new drug targets using genetic libraries to combat multi-drug resistant bacterial strains.
Despite the investment of billions of euros, there has been an inexorable decline in the discovery of new antibiotics over the last decades.
In this individual fellowship (IF) application we propose a strategy to develop bacterial histidine-kinase (HK) inhibitors targeted at the catalytic and ATP-biding domain (CA) as novel broad-spectrum antibacterial (nano)medicines.
Furthermore, putative mechanism of resistance to HK inhibitors and known antibiotics will be studied and novel antibacterial dru…
WAGENINGEN UNIVERSITY
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
