CORDIS Project
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This project investigates the mechanisms of DNA replication in human cells, focusing on identifying novel factors that ensure accurate genome duplication. By employing advanced techniques, it aims to understand how cells respond to replication stress, which is crucial for cancer research and other diseases.
Accurately copying its whole genome is perhaps the most important task of the cell.
Mistakes in DNA replication can result in cell death or, potentially worse, in mutagenesis and genomic instability, which in turn can lead to uncontrolled proliferation, the basis of cancer.
Elucidating the factors involved in DNA replication and understanding the mechanisms by which human cells guarantee the precise duplication of billions of base pairs and thereby appropriate proliferation are of utmost import…
THE FRANCIS CRICK INSTITUTE LIMITED
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