CORDIS Project
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Angiolnc explores the role of long non-coding RNAs and circular RNAs in endothelial cells, which are crucial for vascular health. The project aims to understand how these RNA molecules regulate endothelial function and their potential as therapeutic targets.
Endothelial cells comprise the inner cellular cover of the vasculature, which delivers metabolites and oxygen to the tissue.
Dysfunction of endothelial cells as it occurs during aging or metabolic syndromes can result in atherosclerosis, which can lead to myocardial infarction or stroke, whereas pathological angiogenesis contributes to tumor growth and diabetic retinopathy.
Thus, endothelial cells play central roles in pathophysiological processes of many diseases including cardiovascular diseas…
JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
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