CORDIS Project
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This project investigates how epigenetic changes affect placental development in embryos created through assisted reproductive technologies. It focuses on understanding the relationship between gene expression, methylation, and placental vascular growth to improve outcomes in pregnancies resulting from these techniques…
Normal placental angiogenesis is critical for embryonic survival and development.
Epigenetic modifications, such as methylation of CpG islands, regulate the expression and imprinting of genes.
Epigenetic abnormalities have been observed in embryos from assisted reproductive technologies (ART), which could explain the poor placental vascularisation, embryonic/fetal death, and altered fetal growth in these pregnancies.
Both cloned (somatic cell nuclear transfer, or SNCT) and monoparental (parthoge…
UNIVERSITA DEGLI STUDI DI TERAMO
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