CORDIS Project
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This project investigates helicases, enzymes essential for DNA and RNA processes, to develop new therapeutic drugs targeting human diseases. It combines expertise in physics, chemistry, and biology to enhance understanding of helicase functions and promote collaboration in drug discovery.
Helicases are ubiquitous enzymes, found in viruses, Bacteria, Archaea and eukaryotic cells.
They act as motor proteins to separate or remodel DNA or RNA duplexes, using ATP as an energy source.
Helicases play a key role in a variety of cellular processes, including DNA replication/repair/recombination, as well as RNA translation and transport.
They are emerging as an important class of targets for antiviral, antibiotic and anti-cancer drugs.
To date, several genetic and biochemical studies have…
CONSIGLIO NAZIONALE DELLE RICERCHE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Denmark, Kobenhavn
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Sheffield
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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