CORDIS Project
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This project investigates the antiviral immune mechanisms in the sea anemone Nematostella vectensis, a model organism that diverged 600 million years ago. By studying its RNA interference system, the project aims to uncover insights into the evolution of antiviral immunity in early animals.
Viruses are absolute parasites as their replication depends on biochemical systems of their host.
Because viral infections reduce the fitness of the host organism, hosts and viruses have been tangled in an evolutionary arms race for survival from the very beginning of life.
As the immune system allows organisms to identify and eliminate viral infections, it is of pivotal importance for host fitness.
In vertebrates, the antiviral immunity is heavily based on the interferon pathway that enables in…
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