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The ArcRep project aims to understand how DNA replication occurs by studying the structure of the archaeal replisome. Using advanced imaging techniques, it seeks to reveal the molecular interactions that facilitate DNA copying.
The ability of cells to copy their genome before cell division is one of the wonders of biology.
For DNA replication to succeed, multiple proteins act in concert forming a dynamic molecular engine known as the replisome.
Great effort has been made to characterise all the components of the replisome, yet our understanding of how they work together to achieve DNA replication is still very limited.
Recent studies have provided initial structural clues on the T7 phage, yeast and human replisomes, ye…
INSTITUT PASTEUR
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United States
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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