CORDIS Project
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This project investigates how arenaviruses, which can cause severe diseases in humans, attach to host cells and evade the immune response. By using advanced techniques in structural biology and immunology, the research aims to develop new antiviral therapies and vaccines to combat these viral infections.
Over the last decades, multiple arenaviruses have emerged as zoonotic human pathogens.
They cross the species barrier from their natural rodent hosts to humans and cause severe human disease. A key determinant of viral zoonotic transmission is the ability to bind the receptor molecules displayed on the surface of the host cell.
Despite the threat these viruses cause to public health, little is known of how they infect the host and how they are targeted by the immune response.
Furthermore, the tr…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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