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The ARMOR-T project aims to enhance adoptive T cell therapy for cancer treatment by developing innovative chemokine receptors and modular antibody-activated receptors. It focuses on improving T cell migration and activation in tumors, particularly for pancreatic cancer, with potential applications in other cancer types…
Adoptive T cell therapy (ACT) is a powerful approach to treat even advanced cancer diseases where poor prognosis calls for innovative treatments.
However ACT is critically limited by insufficient T cell infiltration into the tumor, T cell activation at the tumor site and local T cell suppression.
Few advances have been made in the field to tackle these limitations besides increasing T cell activation.
My group has focussed on these unaddressed issues but came to realise that tackling these one b…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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