CORDIS Project
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This project investigates the genetic alterations in embryonal tumors to understand their signaling networks. By combining high-throughput analysis with mathematical modeling, it aims to identify vulnerabilities for new diagnostic and therapeutic strategies.
Cancer is hallmarked by multiple genetic aberrations that lead to a functional derangement of cellular signalling networks.
Embryonal tumours (ETs) comprising neuroblastoma, medulloblastoma and Ewing sarcoma, occur early in life, and thus may reveal pathogenetically relevant lesions clearer than adulthood tumours which carry passenger mutations accumulated during life. ASSET will exploit this fact by focussing on unravelling the signalling networks and their alterations in ETs.
The basic hypothe…
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Austria, Wien
Type: Research institute
Activity type: Research Organisations
SME: No
CEMM - FORSCHUNGSZENTRUM FUER MOLEKULARE MEDIZIN GMBH
Austria, Wien
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
France, Paris
Type: Research institute
Activity type: Research Organisations
SME: No
Germany, Heidelberg
Type: Research institute
Activity type: Research Organisations
SME: No
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