CORDIS Project
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This project investigates how membrane asymmetry and curvature affect the function of membrane proteins and drug transport. It combines experimental and computational methods to understand these interactions at a molecular level.
Real cell membranes are essentially asymmetric and non-planar.
Outer leaflets of the plasma membranes contain neutral lipids and glycolipids, while the inner leaflets host practically all anionic lipids and phosphoinositides.
In addition to asymmetric composition the membranes are usually curved due to spontaneous curvature of the membrane lipids and an influence of membrane proteins and cytoskeleton.
There are many cellular phenomena, which are influenced by the asymmetry and the membrane curva…
INSTITUTE OF PHYSICS OF NATIONAL ACADEMY OF SCIENCE OF UKRAINE
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
France, Besancon
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
INSTITUTE OF SOLID STATE PHYSICS, UNIVERSITY OF LATVIA
Latvia, Riga
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Estonia, Tartu
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Ukraine, Kiev
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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