CORDIS Project
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This project focuses on asthma exacerbations in children, particularly those triggered by human rhinoviruses. It explores the role of innate lymphoid cells in asthma and aims to develop therapies targeting both these immune cells and the viruses to improve treatment outcomes for affected patients.
Asthma exacerbations represent a high unmet medical need in particular in young children.
Human Rhinoviruses (HRV) are the main triggers of these exacerbations.
Till now Th2 cells were considered the main initiating effector cell type in asthma in general and asthma exacerbations in particular.
However, exaggerated Th2 cell activities alone do not explain all aspects of asthma and exacerbations.
Building on our recent discovery of type 2 human innate lymphoid cells (ILC2) capable of promptly pro…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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