CORDIS Project
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The AsymFeCH project aims to develop sustainable iron-catalyzed reactions for the enantioselective synthesis of pharmaceuticals. By replacing precious metals with iron, it seeks to create greener and more cost-effective methods for producing chiral compounds.
The importance of chirality in bioactive molecules is well established with only one enantiomer exhibiting the desired biological activity.
To date, more than 90% of chiral drugs on the market are supplied as racemates potentially causing side-effects or of uncertain bioactivity.
The enantioselective synthesis of chemicals has risen to address such issues with enantioselective catalytic C–H activation standing out due to its atom economy, step efficiency, and avoidance of substrate pre-functiona…
GEORG-AUGUST-UNIVERSITAT GOTTINGEN STIFTUNG OFFENTLICHEN RECHTS
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