CORDIS Project
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This project investigates the role of autotransporter proteins in the biofilm formation and virulence of Pseudomonas aeruginosa, particularly in relation to cystic fibrosis infections. It aims to enhance understanding of bacterial pathogenesis.
Pseudomonas aeruginosa is a major cause of opportunistic infections. P. aeruginosa is found in an estimated 10-20% of all hospital acquired infections; it is implicated in respiratory infections, urinary tract infections, gastrointestinal infections, keratitis, otitis media, and bacteremia.
It is also the predominant cause of morbidity and mortality in cystic fibrosis patients, whose abnormal airway epithelia allow a chronic long-term colonisation of the lungs.
Chronic infections such as this ar…
THE UNIVERSITY OF BIRMINGHAM
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