CORDIS Project
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This project aims to create molecular life in the lab by driving evolvable DNA and RNA machines through nonequilibrium conditions. It explores various replication methods and molecular evolution strategies, mimicking early Earth environments, with potential biotechnological applications.
How can we create molecular life in the lab?That is, can we drive evolvable DNA/RNA-machines under a simple nonequilibrium setting?
We will trigger basic formsof autonomous Darwinian evolution by implementing replication, mutation and selection on the molecular level in a singlemicro-chamber?
We will explore protein-free replication schemes to tackle the Eigen-Paradox of replication and translationunder archaic nonequilibrium settings.
The conditions mimic thermal gradients in porous rock near h…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
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